Dudley Lab
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  • Our Research

    Our research focuses on developing and applying translational and biomedical informatics approaches to harness the digital universe of information towards solving critical challenges in precision medicine and enabling a learning healthcare system.
  • Multiscale Network Modeling of the Immune Systems

    Our lab is developing multiscale network-based approaches to better model and investigate the function and dynamics of immune function across cells, tissues, and broader physiology as well as immune response to environmental stimulus and drug therapies.
  • Drug Discovery and Repurposing

    Our lab is developing and applying integrative computational approaches to discover novel therapeutics and to identify opportunities to repurpose or reposition drugs to address unmet clinical needs.
  • Redefining Human Disease

    Our lab is developing data-driven approaches to redefine human disease and individual health more precisely by combining clinical and molecular data from millions of individuals.
  • About Our Lab

    Our research focuses on the development and use of translational and biomedical informatics approaches to address critical challenges in systems medicine and biomedical informatics. We are interested in identifying and developing novel therapeutic and diagnostic approaches for human disease through integration and analysis of molecular and clinical data, and also perform research to develop and evaluate methods to incorporate genomic sequencing data into clinical practice.
  • Recent Publications

    • Chamaria S, Johnson KW, Vengrenyuk Y, Baber U, Shameer K, Divaraniya AA, Glicksberg BS, Li L, Bhatheja S, Moreno P, Maehara A, Mehran R, Dudley JT, Narula J, Sharma SK, Kini AS. (2017) Intracoronary Imaging, Cholesterol Efflux, and Transcriptomics after Intensive Statin Treatment in Diabetes. Sci Rep. 2017 Aug 1;7(1):7001. doi: 10.1038/s41598-017-07029-7. PMID: 28765529
    • Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green KN, Belfiore R, Winslow W, Oddo S. (2017) Necroptosis activation in Alzheimer's disease. Nat Neurosci. 2017 Jul 24. doi: 10.1038/nn.4608. [Epub ahead of print] PMID: 28758999

    • Salem Omar AM, Shameer K, Narula S, Abdel Rahman MA, Rifaie O, Narula J, Dudley JT, Sengupta PP. (2017) Artificial Intelligence-Based Assessment of Left Ventricular Filling Pressures From 2-Dimensional Cardiac Ultrasound Images. JACC Cardiovasc Imaging. 2017 Jul 13. pii: S1936-878X(17)30468-0. doi: 10.1016/j.jcmg.2017.05.003. [Epub ahead of print] PMID: 28734920
  • Positions Available

    • Postdoctoral Position – Lyme Disease
    • Postdoctoral Position – Skin Conditions
    • Clinical Research Coordinator
  • A Top 20 Medical School

About the Lab

The Dudley Lab is a member of the Institute for Genomics and Multiscale Biology and Department of Genetics and Genomic Sciences at Mount Sinai School of Medicine.

Principal Investigator

Joel Dudley, PhD
Department of Genetics and Genomic Sciences
Tel: 212-659-8656

Dynamic. Creative. Committed.

Icahn School of Medicine at Mount Sinai is proud to stand as a leader in medical and scientific training, biomedical research and patient care.

© 2014 Joel T Dudley Laboratory